Oct 16, 2024
New research highlights the role of advanced glycation end products in diabetes
Siddhartha JanaAdvanced Glycation End Products (AGEs) are harmful compounds formed when proteins and sugars combine under high heat, commonly found in fried and processed foods.
Source: Canva
A clinical trial linked AGE-rich foods to increased inflammation, a key factor in diabetes, contributing to India’s high diabetes rates.
Source: Canva
AGEs can interfere with insulin function, leading to insulin resistance, which is a major contributor to type 2 diabetes development.
Source: Canva
Consuming AGE-rich foods can trigger inflammation that damages tissues, including the pancreas, where insulin is produced.
Source: Canva
AGE-rich foods promote oxidative stress, generating free radicals that damage cells and contribute to diabetes and chronic diseases.
Source: Canva
The study showed that a low-AGE diet, rich in fruits, vegetables, whole grains, and low-fat dairy, can reduce oxidative stress and inflammation in overweight individuals.
Source: Canva
The research was conducted by ICMR and MDRF, aiming to fill gaps in data on AGEs in Indian diets and their cardiometabolic impact.
Source: Canva
Indians are particularly susceptible to insulin resistance and cardiovascular diseases, with AGE-rich diets worsening these risks.
Source: Canva
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